An Experiment Using Human Stem Cells Ended Up Reversing Diabetes in Mice (sciencealert.com)
A technique capable of converting human stem cells into insulin-producing cells could hold huge promise for future diabetic treatments, if results seen in a recent experiment with mice can be successfully replicated in humans.
In a 2020 study, researchers figured out a new way to coax human pluripotent stem cells (hPSCs) into pancreatic beta cells that make insulin. When these insulin-producing cells were transplanted into mice induced to have an acute form of diabetes, their condition was rapidly cured.
"These mice had very severe diabetes with blood sugar readings of more than 500 milligrams per deciliter of blood – levels that could be fatal for a person," explained biomedical engineer Jeffrey R. Millman from Washington University in February last year.
"When we gave the mice the insulin-secreting cells, within two weeks their blood glucose levels had returned to normal and stayed that way for many months."
Wow. Sounds wonderful. Hurry up.
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